Efficacy of ultramicronized Palmitoiletanolamide in add-on to a multi-target treatment of chronic pain. perspective vs retrospective observational study

Abstract Aim: This observational study evaluates the efficacy of ultramicronized-palmitoylethanolamide as add-on therapy to oxycodone/naloxone + pregabalin on the reduction of chronic pain, in comparison with the opioids and anticonvulsant treatment only. Methods: Two groups of patients suffering from chronic pain at spinal or at joint level were considered. One prospective group, consisting of 160 …